Measles, mumps, and rubella combination vaccine
Combines protection against measles, mumps, and rubella in a single injection.
The MMR vaccine protects against three separate diseases. Here's what each one is and why it matters.
| Disease | What parents might notice | How it spreads | Why it can be serious | How vaccination helps |
|---|---|---|---|---|
| Measles | High fever, cough, runny nose, red and watery eyes, followed by a red blotchy rash that usually starts on the face. | Through the air and by contact — measles is one of the most contagious known diseases, and can linger in a room after an infected person leaves. | Can lead to ear infections, pneumonia, and, less commonly, brain swelling (encephalitis) or, rarely, death. Complications are more common in young children. | The vaccine prompts the immune system to recognize the measles virus, providing strong protection after two doses. |
| Mumps | Fever, headache, muscle aches, tiredness, and swelling of the salivary glands, giving puffy cheeks and a swollen jaw. | Saliva and respiratory droplets — coughing, sneezing, and close contact. | Can lead to complications such as inflammation of the testicles or ovaries, inflammation of the brain or its lining, and, in rare cases, hearing loss. | The vaccine helps the immune system recognize and respond to the mumps virus. |
| Rubella (German measles) | Often mild — a low fever and a rash. Some people, especially children, may have no obvious symptoms. | Coughing, sneezing, and close contact. | The greatest danger is to pregnancy: rubella infection in early pregnancy can cause serious birth defects (congenital rubella syndrome). Protecting children helps protect pregnant people in the community. | The vaccine helps prevent rubella infection and reduces its spread, which protects vulnerable pregnancies. |
Why at 12 months? Babies receive some temporary protection against measles from their birthing parent, which can interfere with how well the vaccine works if given too early. By around 12 months, this passed-on protection has usually faded enough for the baby's own immune system to respond well to the vaccine. This is why the first dose is generally given at the first birthday rather than earlier.
Why two doses? One dose provides good protection, but a small percentage of children do not respond fully to the first dose. The second dose helps ensure protection for those children and strengthens it overall. After two doses, protection against measles is very high.
What if a dose is late? If the second dose is delayed, the series does not need to restart — the next dose can generally be given at the next opportunity, following minimum spacing guidelines. A healthcare provider or your local public health unit can confirm the right timing. See the Catch-Up & Missing Records page.
Can it be given with other vaccines? Yes. At the 12-month visit, MMR is routinely given alongside other scheduled vaccines such as pneumococcal conjugate and meningococcal C. Live vaccines like MMR have specific timing considerations relative to certain other live vaccines and to some medical treatments — a healthcare provider can advise if this applies to your child.
This means MMR is one of the more straightforward vaccines when it comes to school requirements — all three diseases it protects against are on the ISPA list, so there is no "partly required" nuance as there is with some combination vaccines.
Reporting: As with all vaccines, parents and caregivers are generally responsible for reporting their child's immunizations to their local public health unit. Healthcare providers do not always do this automatically. After each dose, make sure your provider updates your child's immunization record (the "yellow card"), and report the update to your local public health unit — for example, through Immunization Connect Ontario (ICON) if your area uses it.
Second dose as MMRV: In Ontario, the second dose of measles-mumps-rubella protection is usually given at 4–6 years as the combined MMRV vaccine, which also includes varicella (chickenpox). See the MMRV profile for details on that combination.
Exemptions: If your child cannot receive this vaccine for medical reasons, or you are seeking a non-medical exemption based on conscience or religious belief, see the School Requirements hub for the exemption process.
Two MMR products are authorized for use in Canada: Priorix® (GSK) and M-M-R® II (Merck). Either may be used depending on supply. The information below reflects Priorix®, based on its Health Canada product monograph; M-M-R II contains similar categories of ingredients. The MMR vaccine is a live attenuated vaccine, meaning it contains weakened forms of the viruses that cannot cause the diseases in healthy people.
| Ingredient / Component | Category | Why it's there | Plain-English explanation |
|---|---|---|---|
| Live attenuated measles, mumps, and rubella viruses | Active ingredients | These are weakened forms of the three viruses that train the immune system to recognize them. | "Attenuated" means weakened. These viruses are weakened enough that they don't cause the diseases in healthy people, but they still teach the immune system how to respond if exposed to the real viruses later. |
| Amino acids | Stabilizer / growth component | Support the growth of the vaccine viruses and help keep the vaccine stable. | Amino acids are the building blocks of proteins and are found throughout the body and in food. |
| Lactose | Stabilizer | Helps keep the vaccine stable, particularly during freeze-drying. | A sugar found naturally in milk, used here in a small amount as a stabilizer. |
| Mannitol and sorbitol | Stabilizers | Help protect the vaccine viruses and keep the product stable. | These are sugar alcohols used as stabilizers in many foods and medications. |
| Neomycin (trace amounts) | Manufacturing process residual (antibiotic) | Used during manufacturing to help prevent bacterial contamination of the cell cultures. | A trace amount of this antibiotic may remain. This is relevant for individuals with a known severe allergy to neomycin — discuss this with a healthcare provider if it applies to your child. |
| Water for injection (diluent) | Diluent | Used to reconstitute the freeze-dried vaccine before injection. | Sterile water used to mix the vaccine into its final form just before it's given. |
Expected / common side effects
Timing and duration: Because MMR is a live vaccine, some reactions appear later than with other vaccines — typically about 1 to 2 weeks after the dose, when the weakened viruses prompt an immune response. A mild fever or rash around this time is expected and usually passes within a few days. It is not contagious in the way a true infection would be.
Home care: A cool compress can ease injection-site soreness. Acetaminophen or ibuprofen may be used as directed for fever or discomfort — check with a pharmacist or healthcare provider on appropriate dosing. Children under 19 should not be given ASA (Aspirin) or salicylate-containing products.
When to call a healthcare provider: If a fever is high or persistent, if your child seems unusually unwell, or if you're unsure — it's always reasonable to call.
Mild side effects can happen as the immune system responds. Many children have no side effects at all, and that does not mean the vaccine didn't work.
Rare but important
What clinics do to reduce risk: Clinics ask about allergy history before vaccination and are equipped with epinephrine and trained staff in case of a severe allergic reaction.
Observation period: Many clinics recommend staying nearby for about 15 minutes after vaccination, as severe allergic reactions — though rare — typically occur shortly after the injection.
Get urgent help now if your child has:
If any of these occur, go to the nearest emergency department or call 911. Otherwise, contact a healthcare provider and let them know what happened — this information also helps with vaccine safety monitoring.
Speak with a healthcare provider before this vaccine if:
These usually do NOT require delaying this vaccine:
Where to get it
Typically given by a family doctor or nurse practitioner during routine well-child visits. Some public health units also offer clinics.
What to bring
Your child's immunization record (the "yellow card"), health card if available, and a list of any allergies or previous reactions.
If you're behind
Catching up does not mean restarting. Visit the Catch-Up & Missing Records page or ask your provider for a review.
If records are missing
Contact your local public health unit — they may have records on file, or can advise on next steps.
If vaccinated outside Ontario
Bring any available records to a healthcare provider for review — products and schedules elsewhere may differ slightly from Ontario's.
Contact public health
For record reporting, school requirements, or general questions, see the Resources page for your local public health unit's contact details.
This page is based on:
Please note: This is an independent website. It is not affiliated with, endorsed by, or operated by the Government of Ontario, the Ministry of Health, or any public health unit. The information here is for general education only and is not medical advice — always consult a licensed healthcare provider about your or your child's immunizations.